DelveInsight’s, “Metastatic Prostate Cancer Pipeline Insights, 2023” report provides comprehensive insights about 90+ companies and 110+ pipeline drugs in the metastatic prostate cancer pipeline landscape. It covers the Metastatic Prostate Cancer pipeline drug profiles, including Metastatic Prostate Cancer clinical trials and nonclinical stage products. It also covers the Metastatic Prostate Cancer therapeutics assessment by product type, stage, route of administration, and molecule type. It further highlights the inactive pipeline products in this space.
To explore more information on the latest breakthroughs in the Metastatic Prostate Cancer Pipeline treatment landscape of the report, click here @ Metastatic Prostate Cancer Pipeline Outlook
Metastatic Prostate Cancer Overview
Metastatic Prostate Cancer is a type of prostate cancer which spreads to the other parts of body, i.e., cancer has “metastasized.” Most often, prostate cancer spreads to the bones or lymph nodes. It’s also common for it to spread to the liver or lungs. It’s rarer for it to move to other organs, such as the brain. Metastatic prostate cancer is an advanced form of cancer. There’s no cure, but it can treat it and control it. Most men with advanced prostate cancer live a normal life for many years.
Key Takeaways from the Metastatic Prostate Cancer Pipeline Report
For further information, refer to the detailed Metastatic Prostate Cancer Unmet Needs, Metastatic Prostate Cancer Market Drivers, and Metastatic Prostate Cancer Market Barriers, click here for Metastatic Prostate Cancer Ongoing Clinical Trial Analysis
Metastatic Prostate Cancer Emerging Drugs Profile
FP-001 is a long-acting gonadotropin releasing hormone (GnRH) agonist being developed as Leuprolide Mesylate for Injectable Suspension. It is under development by Foresee Pharmaceuticals and ScinoPharm Joint Venture and is currently in Phase III stage for the treatment of Prostate Cancer. The drug candidate is being developed in different dosage formulations and depending on them, they are in different stages of development.
Relugolix (Pre-registration) is the Myovant’s lead product candidate and is an orally available small molecule, non-peptide gonadotropin-releasing hormone (GnRH or luteinizing hormone-releasing hormone (LHRH)) antagonist, with potential antineoplastic activity. Relugolix competitively binds to and blocks the GnRH receptor in the anterior pituitary gland, which both prevents GnRH binding to the GnRH receptor and inhibits the secretion and release of both luteinizing hormone (LH) and follicle stimulating hormone (FSH).
Atezolizumab (Tecentriq, Phase III) is a novel, anti-PDL1 targeted prescription cancer immunotherapy. It is monoclonal antibody derived from the Chinese hamster ovary cells by recombinant DNA technology. Atezolizumab works by binding to PD-L1 receptor expressed on tumor cells and tumor-infiltrating immune cells and thereby leads to the prevention of binding of PD-L1 receptor to other proteins namely as B7.1 and PD-1. This process leads to the release of PD-1/ PD-L1 mediated inhibition of the immune response, and also causes the activation of anti-tumor immune response without inducing the antibody dependent cellular cytotoxicity (ADCC). As stated by the company, this mode of action may eliminate the “stop sign” that gives the signals to inactivate T-cells. Tecentriq may also affect normal cells.
Darolutamide (Phase III) is an orally administered second generation androgen receptor (AR) antagonist that has a unique chemical structure designed to block the growth of cancer cells through binding to the AR with high affinity and inhibiting the receptor function. In preclinical studies, darolutamide and its main circulating metabolite are active also in known AR mutants (ex W742L, F877L), and have been found to have negligible blood-brain barrier penetration.
DCVAC is an autologous immunotherapy manufactured from a patient’s white blood cells. It is composed of autologous Polyinosinic-Polycytidylic activated dendritic cells pulsed with killed LNCaP prostate cancer cell line. Sotio is currently leading following trials for the treatment of Metastatic prostate cancer-
Phase III: Randomized, Double Blind, Multicenter, Parallel-group, Phase III Study to Evaluate Efficacy and Safety of DCVAC/PCa Versus Placebo in Men with Metastatic Castration Resistant Prostate Cancer Eligible for 1st Line Chemotherapy
Phase I/II: Clinical Trial to Evaluate the Safety and Immune Activation of the Combination of DCVAC/PCa, and ONCOS-102, in Men with Advanced Metastatic Castration-resistant Prostate Cancer
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Metastatic Prostate Cancer Pipeline Therapeutics Assessment
There are approx. 90+ key companies which are developing the therapies for Metastatic Prostate Cancer. The companies which have their Metastatic Prostate Cancer drug candidates in the most advanced stage, i.e. Pre-registration phase include, Foresee Pharmaceuticals and Myovant Biosciences.
Dive deep into rich insights for drugs for Metastatic Prostate Cancer Pipeline, click here @ Metastatic Prostate Cancer Unmet Needs and Analyst Views
Scope of the Metastatic Prostate Cancer Pipeline Report
Got Queries? Find out the related information on Metastatic Prostate Cancer Mergers and acquisitions, Metastatic Prostate Cancer Licensing Activities @ Metastatic Prostate Cancer Emerging Drugs, and Recent Trends
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